Jun Miyake Laboratory

Foresight Deep Intelligence

Graduate School of Engineering, Osaka University​

<2020-2010>

326.   Masahiro Yanagawa, Hirohiko Niioka, Masahiko Kusumoto, Kazuo Awai, Mitsuko Tsubamoto, Yukihisa Satoh, Tomo Miyata, Yuriko Yoshida, Noriko Kikuchi, Akinori Hata, Shoji Kido, Hajime Nagahara, Jun Miyake, Noriyuki Tomiyama, Diagnostic Performance for Pulmonary Invasive Adenocarcinoma on CT: Comparison of Radiologists With and Without Three-dimensional Convolutional Neural Networks.European Radiology, accepted 2020.

325.   Naoki Yamato, Hirohiko Niioka, Jun Miyake, Mamoru Hashimoto, Improvement of nerve imaging speed with coherent anti-Stokes Raman scattering rigid endoscope using deep-learning noise reduction, Scientific Reports accepted 2020年8月. 

324.   Naoki Yamato, Mana Matsuya, Hirohiko Niioka, Jun Miyake, Mamoru Hashimoto, Nerve Segmentation with Deep Learning from Label-Free Endoscopic Images Obtained Using Coherent Anti-Stokes Raman Scattering, Biomolecules 10(7) 1012 - 1012 DOI: 10.3390/biom10071012.

323.   Kiminori Yanagisawa, Masayasu Toratani  Ayumu Asai  Masamitsu Konno  Hirohiko Niioka  Tsunekazu Mizushima, Taroh Satoh  Jun Miyake  Kazuhiko Ogawa  Andrea Vecchione, Yuichiro Doki  Hidetoshi Eguchi and Hideshi Ishii, Convolutional Neural Network Can Recognize Drug Resistance of Single Cancer Cells,  Int. J. Mol. Sci. 2020, 21, 3166; doi:10.3390/ijms21093166.

322.   Kouichi Tachibana, Hiroe Ohnishi, Seyed Mohammad Ali Haghparast, Takanori Kihara, Jun Miyake, Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM, BBRC, 13-DEC-2019, DOI information: 10.1016/j.bbrc.2019.12.044 

321.   Tachibana K, Yamane J, Haghparast SMA, Miyake J.,  Sialomucin and phosphorylated-ERM are inhibitors for cadherin-mediated aggregate formation,  Biochem Biophys Res Commun. 2019 Nov 26;520(1):159-165. doi: 10.1016/j.bbrc.2019.09.128. Epub 2019 Sep 30.

320.   Tatsuya Matsumoto, Hirohiko Niioka, Yasuaki Kumamoto, Junya Sato, Osamu Inamori, Ryuta Nakao, Yoshinori Harada, Eiichi Konishi, Eigo Otsuji, Hideo Tanaka, JunMiyake &TetsuroTakamatsu, Deep-UV excitation fluorescence microscopy for detection of lymph node metastasis using deep neural network, Scientific RepoRtS  (2019) 9:16912, doi.org/10.1038/s41598-019-53405-w

319.   Masahiro Yanagawa, Hirohiko Niioka, Akinori Hata, Noriko Kikuchi, Osamu Honda, Hiroyuki Kurakami, Eiichi Mori, Masayuki Noguchi, Yoshiyuki Watanabe, Jun Miyake, Noriyuki Tomiyama, Application of deep learning (3-dimensional convolutional neural network) for the prediction of pathological invasiveness in lung adenocarcinoma - A preliminary study, Medicine 98:25(e16119)  (2019), DOI: http://dx.doi.org/10.1097/MD.0000000000016119

318.   Miyake J, Kaneshita Y, Asatani S, Tagawa S, Niioka H, Hirano T., Graphical classification of DNA sequences of HLA alleles by deep learning, Human Cell 31:102-5 (2018). (Epub 2018 Jan 11). Doi: 10.1007/s13577-017-0194-6.

317.   Niioka H, Asatani S, Yoshimura A, Ohigashi H, Tagawa S, Miyake J., Classification of C2C12 cells at differentiation by convolutional neural network of deep learning using phase contrast images, Hum Cell 31(1):87-93 (2018). (Epub 2017 Dec 13). Doi: 10.1007/s13577-017-0191-9.

316.   Onoshima D, Kawakita N, Takeshita D, Niioka H, Yukawa H, Miyake J, Baba Y., Measurement of DNA Length Changes Upon CpG Hypermethylation by Microfluidic Molecular Stretching, Cell Medicine 14, 61-66 (2017). (ePub 2016 Sep 14). doi:10.3727/215517916X693087.

315.   Kihara T, Sugimoto Y, Shinohara S, Takaoka S, Miyake J., Cysteine-rich protein 2 accelerates actin filament cluster formation. PLoS One. 12(8):e0183085. (2017 Aug 16). Doi: 10.1371/journal.pone.0183085.

314.   Kihara T, Kashitani K, Miyake J., In silico characterization of cell-cell interactions using a cellular automata model of cell culture. BMC Res Notes 10:283(15pages)  (2017 July 14). Doi: 10.1186/s13104-017-2613-x.

313.   Daiki Sato, Masahito Yamanaka, Taichi Furukawa, Hirohiko Niioka, Jun Miyake, Norihiko Nishizawa, “Fluorescence imaging using up-conversion fluorescence emission in 480-nm wavelength region from Y2O3:Tm,Yb nanoparticle” The 6th Advanced Lasers and Photon Sources (ALPS’17) (Yokohama, Japan, Apr. 18 - Apr. 21, 2017.

312.   Adiba, A. I., Tanaka, N., Miyake, J., An Adjustable Gaze Tracking System and Its Application for Automatic Discrimination of Interest Objects, IEEE/ASME Transactions on Mechatronics 2016, Volume: 21, Issue: 2, pp. 973 - 979, 

311.   Doan Thi Kim Dung, Shoichiro Fukushima, Taichi Furukawa, Hirohiko Niioka, Takumi Sannomiya, Kaori Kobayashi, Hiroshi Yukawa, Yoshinobu Baba, Mamoru Hashimoto, and Jun Miyake, “Multispectral emissions of lanthanides doped gadolinium oxide nanophosphors for cathodeluminescence and upconversion/down conversion imaging”, Nanomaterials 6, e163(P1-17) (2016 Sep 6). Doi: 10.3390/nano6090163.

310.   Fukushima, S., Furukawa, T., Niioka, H., Ichimiya, M., Sannnomiya, T., Miyake, J., Ashida, M., Araki, T. and Hashimoto, M., “Synthesis of Y2O3 nanophosphors by homogeneous precipitation method using excessive urea for cathodoluminescence and upconversion luminescence bioimaging”, Optical Materials Express, 6, 831-843 (2016). DOI:10.1364/OME.6.000831.

309.   Fukushima, S., Furukawa, T., Niioka, H., Ichimiya, M., Sannomiya, T., Tanaka, N., Onoshima, D., Yukawa, H., Baba, Y., Ashida, M., Miyake, J., Araki, T., and Hashimoto, M., “Near-infrared and cathodoluminescence nanophosphors for correlative multi-scale bioimaging”, Scientific Reports 6:25950, (2016). DOI: 10.1038/srep25950.

308.   Hirohiko Niioka, Jumpei Yamasaki, Doan Thi Kim Dung, Jun Miyake, Enhancement of Near-infrared Luminescence of Y2O3:Ln, Yb (Ln = Tm, Ho, Er) by Li-ion Doping for Cellular Bioimaging, Chemistry Lett. 2016, 45, 1406-1408 (2016). Doi:10.1246/cl.160754.  https://link.springer.com/journal/11164/42/11/page/1

307.   Naoki Ikenaga, Saki Okamura, Ken Shibata, Nobuyuki Tanaka, Jun Miyake, The time-series evaluation of biohydrogen production by photosynthetic bacteria under fluctuating illumination pattern, Research on Chemical Intermediates 42, 7701-7711 (2016). https://link.springer.com/journal/11164/42/11/page/1

306.   Daisuke Takagi, Saki Okamura, Kota Tanaka, Naoki Ikenaga, Masayuki Iwashima, Seyed Mohammad Ali Haghparast, Nobuyuki Tanaka, Jun Miyake, Characterization of hydrogen production by the co-culture of dark-fermentative and photosynthetic bacteria, Research on Chemical Intermediates 42, 7713-7722 (2016). https://link.springer.com/journal/11164/42/11/page/1

305.   Kota Tanaka, Saki Okamura, Ken Shibata, Naoki Ikenaga, Nobuyuki Tanaka, Kazumi Hakamada, Jun Miyake, Evaluating a time-delay of hydrogen production quantitatively in photosynthetic bacteria for stabilizing intermittency, Research on Chemical Intermediates 42, 7723-7730 (2016). https://link.springer.com/journal/11164/42/11/page/1

304.   Furukawa T, Fukushima S, Niioka H, Yamamoto N, Miyake J, Araki T, Hashimoto M., Rare-earth-doped nanophosphors for multicolor cathodoluminescence nanobioimaging using scanning transmission electron microscopy, J Biomed Opt. 20(5):56007(6pages) (2015), DOI: 10.1117/1.JBO.20.5.056007.

303.   Haghparast S. M. A., Kihara T, Miyake J., Distinct mechanical behavior of HEK293 cells in adherent and suspended states., PeerJ. 3:1131(13pages) (2015), DOI 10.7717/peerj.1131.

302.   Nobuyuki Tanaka, Yuji Haraguchi, Tatsuya Shimizu, Masayuki Yamato, Teruo Okano, and Jun Miyake, Massively-Multicellular Alignment with the Self-Aggregate of Air Bubbles, 37th IEEE EngMedBiolSoc (EMBC) PP3537-40, 978-1-4244-9270-1/15/(2015). doi: 10.1109/EMBC.2015.7319156. 

301.   Reiko Onuki-Nagasaki, Akira Nagasaki1, Kazumi Hakamada, Taro QP Uyeda, Masato Miyake, Jun Miyake and Satoshi Fujita, Identification of kinases and regulatory proteins required for cell migration using a transfected cell-microarray system, BMC Genetics 16e9(12pages) (2015), DOI 10.1186/s12863-015-0170-7.

300.   Tachibana, K., Haghparast, S.M.A. and Miyake J., Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin, Cell Adhesion & Migration 9, 502-12 (2015). doi: 10.1080/19336918.2015.1113366.

299.   金下裕平,杉山佳奈子, 浅谷学嗣,新岡宏彦, 平野 隆,三宅 淳, Deep Learning を用いたヒトミトコンドリアDNAの分類, Proc. 16th SICE System Integration Division Annual Conference, 2015 Nagoya Dec. 14-16, pp. 1267-1270. 

298.   浅谷学嗣、三宅 淳, Deep Learningを用いた動画特徴量の分析, Proc. 16th SICE System Integration Division Annual Conference, 2015 Nagoya Dec. 14-16, pp. 2667-2671.

297.   Tanaka N, Haraguchi Y, Shimizu T, Yamato M, Okano T, Miyake J., Massively-multicellular alignment with the self-aggregate of air bubbles, 37th Conf Proc IEEE Eng Med Biol Soc. (EMBC), 2015, pp. 3537-40

296.   Niioka H, Fukushima S, Ichimiya M, Ashida M, Miyake J, Araki T, Hashimoto M., Correlative cathodoluminescence and near-infrared fluorescence imaging for bridging from nanometer to millimeter scale bioimaging., Microscopy (Oxf) 63 Suppl 1:i29 (2014).

295.   Adiba, A. I., Tanaka, N., Miyake, J., Intention-shared user-interface by the auto-discrimination of gaze object “See what i see”, MHS <Micro-NanoMechatronics and Human Science> 2014, pp. 1 – 3.

294.   Fukushima, S., Furukawa, T., Niioka, H., Ichimiya, M., Miyake, J., Ashida,M., Araki, T. and Hashimoto, M., Y2O3:Tm,Yb Nanophosphors for Correlative Upconversion Luminescence and Cathodoluminescence Imaging, Micron 67, 90-95 (2014). doi.org/10.1016/j.micron.2014.07.002.

293.   Han, S.W., Morita, K., Simona, P., Kihara, T., Miyake, J., Banu, M., Adachi, T., Probing Actin Filament and Binding Protein Interaction Using an Atomic Force Microscopy, J. Nanosci. Nanotech. 14, 5654-5657 (2014). doi:10.1166/jnn.2014.8777.

292.   Nakaya Y, Shide K, Naito H, Niwa T, Horio T, Miyake J, Shimoda K., Effect of NS-018, a selective JAK2V617F inhibitor, in a murine model of myelofibrosis, Blood Cancer Journal. 4, e174(6pages) (2014). doi:10.1038/bcj.2013.73.

291.   Sun Q, Chen M, Miyake J, Qian DJ., Fabrication and characterization for the nanoconjugates of pyridyldithio-functionalized multiwalled carbon nanotubes and cytochrome c in Langmuir-Blodgett films. J Nanosci Nanotechnol. 14, 5468-72 (2014). doi:10.1166/jnn.2014.8422.

290.   Tanaka, N., Ota, H., Fukumori, K., Miyake, J., Yamato, M. and Okano, T., Micro-patterned cell-sheets fabricated with stamping-force-controlled micro-contact printing, Biomaterials 35, 9801-10 (2014).  doi.org/10.1016/j.biomaterials.2014.08.043.

289.   Shintaku H., Hakamada K, Miyake J., Kawano S., Measurement of local electric field in microdevices for low-voltage electroporation of adherent cells, Microsyst Technol. 20, 303-13 (2014). DOI 10.1007/s00542-013-1797-9.

288.   Tanaka, N., Ota, H.. Fukumori, K., Yamato M, Okano T, Miyake J., Noncontact fine alignment for multiple microcontact printing, IROS 2014 <Intelligent Robots and Systems> IEEE/RSJ International Conference, 2014 pp. 828 - 833

287.   Tanaka, N., Kondo, M., Sugiyama, H., Yamato, M., Okano, T., Miyake, J. Surface-tension microscopy by noncontact meniscus-manipulation, MHS <Micro-NanoMechatronics and Human Science> 2014 International Symposium, pp. 1 - 2

286.   Tanaka, N., Haraguchi, Y., Shimizu, T., Yamato, M., Okano, T., Miyake, J., High-throughput cell-patterning with a self-assembled bubble-raft, MHS <Micro-NanoMechatronics and Human Science> 2014, pp. 1 - 2.

285.   Adiba, A. I., Hatta, K., Baba, R., Kaneda, T., and Miyake, J.,‘See What I See’ sharing the cognition with an intelligent machine, System Integration (SII), 2013 IEEE/SICE International Symposium 2013, pp.388-392. DOI: 10.1109/SII.2013.6776629

284.   Haghparast S. M. A., Kihara T, Shimizu Y, Yuba S, Miyake J., Actin-based biomechanical features of suspended normal and cancer cells. J Biosci Bioeng. 116, 380-5 (2013).  doi.org/10.1016/j.jbiosc.2013.03.003.

283.   Hakamada K, Shintaku H, Nagata T, Fujimoto H, Kawano S, Miyake J., Development of a microfabricated device for low-voltage electropermeabilization of adherent cells, J Biosci Bioeng. 115, 314-9 (2013).   doi.org/10.1016/j.jbiosc.2012.10.005.

282.   Kihara T, Ito J, Miyake J., Measurement of biomolecular diffusion in extracellular matrix condensed by fibroblasts using fluorescence correlation spectroscopy. PLoS One. 8(11)e82382(8pages) (2013).  doi:10.1371/journal.pone.0082382.

281.   Kihara, T., Yoshida, T., Haghparast, S.M.A., Miyake, J., Elasticity mapping analysis of apical cell periphery actin structures of normal fibroblasts and cervical cancer cells, J. Analytical Sciences, Methods and Instrumentation, 3 (2), 124-129 (2013). doi.org/10.4236/jasmi.2013.32015. 

280.   Shinohara, S., Kihara, T., Sakai, S., Matsusaki, M., Akashi, M., Taya, M., Miyake, J., Fabrication of in vitro three-dimensional multilayered blood vessel model using human endothelial and smooth muscle cells and high-strength PEG hydrogel, J. Biosci. Bioeng., 116, 231-234 (2013) .  doi.org/10.1016/j.jbiosc.2013.02.013

279.   Silberberg Y. R., Mieda S, Amemiya Y, Sato T, Kihara T, Nakamura N, Fukazawa K, Ishihara K, Miyake J, Nakamura C., Evaluation of the actin cytoskeleton state using an antibody-functionalized nanoneedle and an AFM, Biosens Bioelectron. 40, 3-9 (2013).  doi.org/10.1016/j.bios.2012.06.044

278.   Yamaguchi S, Komiya S, Matsunuma E, Yamahira S, Kihara T, Miyake J, Nagamune T., Transfer printing of transfected cell microarrays from poly(ethylene glycol)-oleyl surfaces onto biological hydrogels. Biotechnol Bioeng. 110, 3269-74 (2013).  DOI: 10.1002/bit.25010

277.   Adiba, A. I., Hatta, K., Baba, R., Kaneda, T., and Miyake, J.,‘See What I See’ shar-ing the cognition with an intelligent machine, System Integration (SII), 2013 IEEE/SICE International Symposium 2013, pp.388 - 393.

276.   Hakamada K, Miyake J., Evaluation method for gene transfection by using the period of onset of gene expression and cell division., J Biosci Bioeng. 113, 124-7 (2012).

275.   Mieda S, Amemiya Y, Kihara T, Okada T, Sato T, Fukazawa K, Ishihara K, Nakamura N, Miyake J, Nakamura C., Mechanical force-based probing of intracellular proteins from living cells using antibody-immobilized nanoneedles, Biosens Bioelectron. 31, 323-9 (2012).

274.   Ojima Y, Hakamada K, Nishinoue Y, Nguyen M. H, Miyake J, Taya M., Motility behavior of rpoS-deficient Escherichia coli analyzed by individual cell tracking. J Biosci Bioeng. 114, 652-656 (2012).

273.   Sakai S, Inagaki H, Liu Y, Matsuyama T, Kihara T, Miyake J, Kawakami K, Taya M., Rapidly serum-degradable hydrogel templating fabrication of spherical tissues and curved tubular structures. Biotechnol Bioeng. 109, 2911-2919 (2012). 

272.   Shimizu Y., Haghparast S. M.A., Kihara T., Miyake J., Cortical rigidity of round cells in mitotic phase and suspended state. Micron 43 1246–1251 (2012).

271.   Shimizu Y., Kihara T., Haghparast S. M.A., Yuba S., Miyake J., Simple display system of mechanical properties of cells and their dispersion. PLoS One 7: e34305 (2012).  

270.   Han, S.W., Mieda, S., Nakamura, C., Kihara, T., Nakamura, N., Miyake, J., Successive detection of insulin-like growth factor-II bound to receptors on a living cell surface using an AFM.  J. Mol. Recognit., 24, 17-22 (2011).  (ePub 2009 Dec. 1)

269.   Kihara T., Shinohara S., Fujikawa R., Sugimoto Y., Murata M., Miyake J., Regulation of cysteine-rich protein 2 localization by the development of actin fibers during smooth muscle cell differentiation., Biochem Biophys Res Commun. 411, 96-101 (2011).

268.   Kihara T., Haghparast S.M.A., Shimizu Y., Yuba S., Miyake J., Physical properties of mesenchymal stem cells are coordinated by the perinuclear actin cap, Biochem Biophys Res Commun. 409, 1-6. (2011).

267.   Kihara T., Zhang Y., Hu Y., Mao Q., Tang Y., Miyake J., Effect of composition, morphology and size of nanozeolite on its in vitro cytotoxicity., J. Biosci Bioeng. 111, 725-30 (2011).

266.   Kihara, T., Liu, X.Y,. Nakamura, C., Park, K.M., Han, S.W., Qian, D.J., Kawasaki, K., Zorin, H.A., Yasuda, S., Hata, K., Wakayama, T., and Miyake, J., Direct electron transfer to hydrogenase for catalytic hydrogen production using a single-walled carbon nanotube forest, Int. J. Hydrogen Energy 36, 7523-7529 (2011).

265.   Odahara, T., Ishii, N., Ooishi, A., Honda, S., Uedaira, H,. Hara, M,. Miyake, J., Thermostability of Rhodopseudomonas viridis and Rhodospirillum rubrum chromatophores reflecting physiological conditions, Biochim. Biophys. Acta, 1808, 1645-53 (2011).

264.   Ogawa S, Tokumoto Y, Miyake J, Nagamune T.,Immunopanning selection of A2B5-positive cells increased the differentiation efficiency of induced pluripotent stem cells into oligodendrocytes. Neurosci Lett. 489, 79-83 (2011).

263.   Ogawa S, Tokumoto Y, Miyake J, Nagamune T., Induction of oligodendrocyte differentiation from adult human fibroblast-derived induced pluripotent stem cells., In Vitro Cell Dev Biol Anim. 47, 464-9 (2011).

262.   Ohto-Fujita E, Konno T, Shimizu M, Ishihara K, Sugitate T, Miyake J, Yoshimura K, Taniwaki K, Sakurai T, Hasebe Y, Atomi Y., Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts. Cell Tissue Res. 345, 177-90 (2011).

261.   Wang HL, Sun Q, Chen M, Miyake J, Qian DJ., Layer-by-layer assembly and characterization of multilayers of a manganese porphyrin linked poly(4-vinylpyridinium) derivative and poly(styrenesulfonic acid-o-maleic) acid., Langmuir. 27, 9880-9 (2011).